chrom
stringclasses 2
values | pos
int64 10.2k
249M
| ref
stringclasses 4
values | alt
stringclasses 4
values | AC
int64 1
152k
| AN
int64 2
152k
| AF
float64 0
1
| consequence
stringlengths 9
552
| GPN-MSA
float32 -13.59
11.1
|
|---|---|---|---|---|---|---|---|---|
1 | 15,260 | C | T | 1 | 88,216 | 0.000011 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.518254 |
1 | 15,283 | A | G | 11 | 63,580 | 0.000173 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.015153 |
1 | 15,329 | G | A | 7 | 109,212 | 0.000064 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -0.550674 |
1 | 15,343 | G | T | 3 | 126,728 | 0.000024 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.461903 |
1 | 15,369 | C | T | 1 | 144,370 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.287459 |
1 | 15,430 | C | T | 1 | 150,016 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.468587 |
1 | 15,433 | C | T | 1 | 150,038 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.194169 |
1 | 15,447 | A | G | 5,112 | 118,406 | 0.043173 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.35779 |
1 | 15,458 | G | A | 1 | 149,888 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.393013 |
1 | 15,499 | C | A | 1 | 147,436 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.405091 |
1 | 15,554 | T | C | 3 | 141,282 | 0.000021 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.325508 |
1 | 15,557 | G | A | 2 | 142,654 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.246111 |
1 | 15,557 | G | T | 1 | 142,652 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.421993 |
1 | 15,560 | A | C | 1 | 142,814 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.615949 |
1 | 15,584 | T | C | 337 | 147,612 | 0.002283 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.146266 |
1 | 15,585 | G | A | 603 | 147,746 | 0.004081 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.609584 |
1 | 15,602 | G | A | 2 | 150,532 | 0.000013 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.364514 |
1 | 15,603 | G | A | 2 | 150,600 | 0.000013 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.103861 |
1 | 15,616 | G | A | 2,724 | 144,478 | 0.018854 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.40971 |
1 | 15,627 | T | C | 1 | 151,788 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.460141 |
1 | 15,630 | G | T | 1 | 151,910 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.370191 |
1 | 15,631 | G | A | 8 | 151,894 | 0.000053 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.331625 |
1 | 15,634 | C | T | 52 | 151,064 | 0.000344 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.079412 |
1 | 15,637 | T | A | 1 | 151,914 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.8195 |
1 | 15,639 | G | C | 1 | 151,804 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.041492 |
1 | 15,643 | C | T | 83 | 151,208 | 0.000549 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.080123 |
1 | 15,659 | G | A | 2 | 152,056 | 0.000013 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.428714 |
1 | 15,659 | G | C | 1 | 152,056 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.575752 |
1 | 15,666 | C | T | 8 | 151,854 | 0.000053 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.382073 |
1 | 15,701 | G | C | 30 | 151,976 | 0.000197 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.142052 |
1 | 15,704 | G | A | 1 | 152,044 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.983526 |
1 | 15,723 | T | C | 1 | 151,298 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.788495 |
1 | 15,727 | C | T | 1 | 151,188 | 0.000007 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.274242 |
1 | 15,747 | G | A | 2 | 148,924 | 0.000013 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.224398 |
1 | 15,761 | A | G | 3 | 144,558 | 0.000021 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 1.509154 |
1 | 15,762 | G | C | 2 | 144,234 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.192862 |
1 | 15,769 | C | T | 5 | 140,714 | 0.000036 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.367447 |
1 | 15,776 | A | T | 118 | 135,128 | 0.000873 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 1.006779 |
1 | 15,777 | A | G | 133 | 129,312 | 0.001029 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 2.881871 |
1 | 15,787 | C | T | 3 | 129,224 | 0.000023 | TF_binding_site_variant,downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.302688 |
1 | 15,817 | G | T | 1 | 104,268 | 0.00001 | TF_binding_site_variant,downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.404229 |
1 | 15,833 | T | C | 1 | 98,706 | 0.00001 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | 1.07539 |
1 | 15,834 | C | T | 5 | 98,588 | 0.000051 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.707644 |
1 | 15,835 | G | A | 37 | 97,112 | 0.000381 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.567784 |
1 | 15,835 | G | C | 1 | 97,176 | 0.00001 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -4.919255 |
1 | 15,837 | T | C | 1 | 97,156 | 0.00001 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -6.388683 |
1 | 15,840 | T | C | 2 | 96,736 | 0.000021 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -5.18974 |
1 | 15,848 | G | A | 1 | 93,760 | 0.000011 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -3.611547 |
1 | 15,849 | C | T | 44 | 93,484 | 0.000471 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.687604 |
1 | 15,854 | C | A | 15 | 90,392 | 0.000166 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -5.411034 |
1 | 15,865 | C | T | 4 | 75,740 | 0.000053 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.618858 |
1 | 15,866 | G | A | 1 | 73,840 | 0.000014 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -0.929918 |
1 | 15,876 | G | C | 5 | 63,410 | 0.000079 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -6.89871 |
1 | 15,877 | C | T | 1 | 62,178 | 0.000016 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -5.582259 |
1 | 15,883 | G | A | 3 | 56,406 | 0.000053 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.334878 |
1 | 15,886 | T | C | 1 | 53,354 | 0.000019 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -5.452936 |
1 | 15,891 | T | C | 1 | 49,476 | 0.00002 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -7.105263 |
1 | 15,893 | T | C | 3 | 48,452 | 0.000062 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | 3.675432 |
1 | 15,895 | G | A | 12 | 48,008 | 0.00025 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -4.367438 |
1 | 15,906 | A | T | 1 | 71,890 | 0.000014 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -3.157152 |
1 | 15,912 | C | T | 8 | 87,974 | 0.000091 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | 3.949215 |
1 | 15,913 | G | A | 24 | 88,082 | 0.000272 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.503983 |
1 | 15,920 | T | G | 1 | 89,744 | 0.000011 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -6.77264 |
1 | 15,922 | A | G | 143 | 90,458 | 0.001581 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -2.257965 |
1 | 15,929 | T | A | 2 | 96,148 | 0.000021 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -8.497154 |
1 | 15,932 | C | A | 5 | 97,744 | 0.000051 | downstream_gene_variant,non_coding_transcript_exon_variant,regulatory_region_variant | -4.097515 |
1 | 15,956 | G | A | 32 | 104,968 | 0.000305 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.300979 |
1 | 15,973 | G | A | 2 | 110,404 | 0.000018 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.303981 |
1 | 15,973 | G | C | 2 | 110,406 | 0.000018 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.555987 |
1 | 15,986 | G | C | 5 | 113,076 | 0.000044 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.822503 |
1 | 15,989 | G | C | 150 | 113,660 | 0.00132 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.936023 |
1 | 15,992 | C | G | 2 | 113,952 | 0.000018 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.175169 |
1 | 15,994 | G | C | 1 | 114,392 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.442233 |
1 | 15,995 | G | A | 1 | 114,516 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.963168 |
1 | 15,999 | G | T | 1 | 115,120 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.169176 |
1 | 16,006 | G | A | 1 | 115,944 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.086306 |
1 | 16,014 | C | T | 246 | 109,726 | 0.002242 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.30999 |
1 | 16,021 | C | T | 1 | 118,752 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.376328 |
1 | 16,030 | G | A | 4 | 119,910 | 0.000033 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.518686 |
1 | 16,033 | G | A | 3 | 120,010 | 0.000025 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.41624 |
1 | 16,035 | G | A | 1 | 120,304 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.705029 |
1 | 16,037 | G | A | 2 | 120,444 | 0.000017 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.257416 |
1 | 16,037 | G | T | 1 | 120,444 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -2.81845 |
1 | 16,042 | G | T | 7 | 120,780 | 0.000058 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.40251 |
1 | 16,046 | C | T | 1 | 121,072 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.757364 |
1 | 16,050 | C | T | 1 | 121,392 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.320309 |
1 | 16,059 | G | A | 1 | 121,844 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.602282 |
1 | 16,062 | G | A | 19 | 121,948 | 0.000156 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.257719 |
1 | 16,064 | G | A | 2 | 122,176 | 0.000016 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.30666 |
1 | 16,070 | C | T | 5 | 122,672 | 0.000041 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.010069 |
1 | 16,071 | G | A | 326 | 122,512 | 0.002661 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.361584 |
1 | 16,079 | G | C | 10 | 123,178 | 0.000081 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.659377 |
1 | 16,080 | G | C | 1 | 123,172 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.313421 |
1 | 16,082 | C | T | 7 | 123,066 | 0.000057 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | 0.449674 |
1 | 16,083 | G | A | 8 | 123,272 | 0.000065 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.148463 |
1 | 16,091 | G | A | 29 | 123,618 | 0.000235 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.546213 |
1 | 16,094 | G | C | 1 | 123,942 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.600115 |
1 | 16,097 | T | G | 2 | 124,116 | 0.000016 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.279563 |
1 | 16,098 | G | C | 2 | 124,070 | 0.000016 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -1.531112 |
1 | 16,104 | G | A | 5 | 120,814 | 0.000041 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,regulatory_region_variant | -0.692453 |