chrom
stringclasses 2
values | pos
int64 10.2k
249M
| ref
stringclasses 4
values | alt
stringclasses 4
values | AC
int64 1
152k
| AN
int64 2
152k
| AF
float64 0
1
| consequence
stringlengths 9
552
| GPN-MSA
float32 -13.59
11.1
|
|---|---|---|---|---|---|---|---|---|
1 | 14,005 | G | T | 2 | 58,304 | 0.000034 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.631493 |
1 | 14,065 | T | C | 1 | 52,702 | 0.000019 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.557891 |
1 | 14,092 | G | C | 1 | 57,812 | 0.000017 | downstream_gene_variant,non_coding_transcript_exon_variant | -3.860126 |
1 | 14,133 | G | C | 481 | 71,618 | 0.006716 | downstream_gene_variant,non_coding_transcript_exon_variant | 0.113745 |
1 | 14,152 | T | A | 1 | 79,266 | 0.000013 | downstream_gene_variant,non_coding_transcript_exon_variant | -5.156605 |
1 | 14,156 | A | G | 31 | 80,698 | 0.000384 | downstream_gene_variant,non_coding_transcript_exon_variant | -4.078667 |
1 | 14,157 | G | C | 24 | 80,750 | 0.000297 | downstream_gene_variant,non_coding_transcript_exon_variant | -5.32298 |
1 | 14,184 | C | T | 1 | 90,290 | 0.000011 | downstream_gene_variant,non_coding_transcript_exon_variant | -5.10689 |
1 | 14,185 | T | A | 1 | 90,324 | 0.000011 | downstream_gene_variant,non_coding_transcript_exon_variant | -5.40838 |
1 | 14,192 | G | A | 1 | 90,398 | 0.000011 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.667471 |
1 | 14,283 | G | A | 1 | 90,498 | 0.000011 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.862302 |
1 | 14,302 | C | T | 1 | 88,992 | 0.000011 | downstream_gene_variant,non_coding_transcript_exon_variant | -0.37364 |
1 | 14,335 | G | A | 3 | 102,986 | 0.000029 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.960174 |
1 | 14,371 | G | C | 2 | 120,010 | 0.000017 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.628531 |
1 | 14,374 | A | G | 1 | 120,286 | 0.000008 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.019032 |
1 | 14,383 | T | G | 5 | 122,952 | 0.000041 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.829815 |
1 | 14,388 | A | G | 8 | 125,004 | 0.000064 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.697217 |
1 | 14,390 | A | G | 1 | 125,358 | 0.000008 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.489717 |
1 | 14,392 | G | T | 1 | 126,556 | 0.000008 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.539652 |
1 | 14,402 | G | A | 1 | 130,272 | 0.000008 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.934962 |
1 | 14,402 | G | C | 1 | 130,272 | 0.000008 | downstream_gene_variant,non_coding_transcript_exon_variant | -3.056448 |
1 | 14,409 | G | A | 2 | 131,490 | 0.000015 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.521881 |
1 | 14,410 | C | A | 2 | 131,614 | 0.000015 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.535773 |
1 | 14,422 | T | A | 1 | 133,246 | 0.000008 | downstream_gene_variant,non_coding_transcript_exon_variant | -5.577738 |
1 | 14,424 | G | A | 8 | 133,528 | 0.00006 | downstream_gene_variant,non_coding_transcript_exon_variant | -4.929765 |
1 | 14,428 | G | C | 1 | 133,832 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | 3.121487 |
1 | 14,433 | G | C | 1 | 134,356 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -0.938078 |
1 | 14,434 | C | T | 2 | 134,404 | 0.000015 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.234975 |
1 | 14,435 | C | T | 4 | 134,196 | 0.00003 | downstream_gene_variant,non_coding_transcript_exon_variant | 1.341203 |
1 | 14,437 | T | A | 1 | 134,772 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.276581 |
1 | 14,439 | T | G | 2 | 135,426 | 0.000015 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.205585 |
1 | 14,449 | G | C | 1 | 135,962 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.513948 |
1 | 14,450 | C | A | 1 | 136,080 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -0.340513 |
1 | 14,457 | A | G | 3 | 136,680 | 0.000022 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.260973 |
1 | 14,462 | A | G | 1 | 137,408 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.114422 |
1 | 14,464 | A | T | 26,287 | 133,502 | 0.196903 | downstream_gene_variant,non_coding_transcript_exon_variant | 0.895136 |
1 | 14,468 | G | C | 1 | 138,406 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.559853 |
1 | 14,469 | C | T | 349 | 138,458 | 0.002521 | downstream_gene_variant,non_coding_transcript_exon_variant | 1.11251 |
1 | 14,470 | G | A | 595 | 129,638 | 0.00459 | downstream_gene_variant,non_coding_transcript_exon_variant | 0.154884 |
1 | 14,471 | C | T | 11 | 139,634 | 0.000079 | downstream_gene_variant,non_coding_transcript_exon_variant | -0.100992 |
1 | 14,487 | G | A | 140 | 139,038 | 0.001007 | downstream_gene_variant,non_coding_transcript_exon_variant | 0.717221 |
1 | 14,492 | C | G | 2 | 141,726 | 0.000014 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.31629 |
1 | 14,496 | T | G | 2 | 141,916 | 0.000014 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.189727 |
1 | 14,498 | G | T | 1 | 137,794 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant | -1.551375 |
1 | 14,506 | G | A | 58 | 142,218 | 0.000408 | downstream_gene_variant,non_coding_transcript_exon_variant,splice_region_variant&intron_variant&non_coding_transcript_variant | -1.498619 |
1 | 14,509 | G | C | 1 | 142,396 | 0.000007 | downstream_gene_variant,non_coding_transcript_exon_variant,splice_region_variant&intron_variant&non_coding_transcript_variant | -1.11418 |
1 | 14,513 | G | A | 11 | 142,154 | 0.000077 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.492475 |
1 | 14,631 | G | C | 1 | 136,454 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.620149 |
1 | 14,632 | G | C | 2 | 136,418 | 0.000015 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.538155 |
1 | 14,643 | G | A | 5 | 136,256 | 0.000037 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -0.237455 |
1 | 14,647 | G | C | 2 | 136,268 | 0.000015 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.669824 |
1 | 14,656 | C | A | 2 | 139,720 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.242997 |
1 | 14,661 | G | A | 2 | 140,530 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.261999 |
1 | 14,671 | G | C | 1,269 | 141,098 | 0.008994 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.262214 |
1 | 14,671 | G | T | 2 | 141,568 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -0.969068 |
1 | 14,673 | G | C | 416 | 140,650 | 0.002958 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -1.361694 |
1 | 14,687 | T | C | 2 | 145,110 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -0.076163 |
1 | 14,696 | C | T | 3 | 145,666 | 0.000021 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -3.973517 |
1 | 14,711 | G | A | 289 | 145,338 | 0.001988 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -0.066131 |
1 | 14,716 | C | T | 2 | 147,472 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -4.128562 |
1 | 14,719 | C | A | 5 | 147,596 | 0.000034 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -8.405299 |
1 | 14,728 | C | A | 3 | 147,918 | 0.00002 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -6.890034 |
1 | 14,731 | G | A | 1 | 148,066 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -5.210156 |
1 | 14,738 | C | G | 15 | 148,174 | 0.000101 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -6.074197 |
1 | 14,749 | G | A | 2 | 148,770 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -5.175336 |
1 | 14,754 | G | C | 2 | 148,788 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -5.524389 |
1 | 14,776 | G | A | 9 | 148,638 | 0.000061 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -2.376425 |
1 | 14,776 | G | C | 1 | 148,644 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -5.194462 |
1 | 14,778 | G | A | 2 | 148,550 | 0.000013 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -4.630152 |
1 | 14,798 | C | G | 28 | 146,644 | 0.000191 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -3.0803 |
1 | 14,819 | C | T | 2 | 144,448 | 0.000014 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -2.475646 |
1 | 14,896 | T | C | 168 | 137,362 | 0.001223 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.227699 |
1 | 14,916 | C | T | 1 | 132,384 | 0.000008 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.531273 |
1 | 14,933 | G | A | 1,203 | 111,878 | 0.010753 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.24024 |
1 | 14,948 | G | A | 970 | 115,950 | 0.008366 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | 1.168899 |
1 | 14,976 | G | A | 624 | 101,128 | 0.00617 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -3.147697 |
1 | 14,982 | T | A | 2 | 110,174 | 0.000018 | downstream_gene_variant,intron_variant&non_coding_transcript_variant,non_coding_transcript_exon_variant | -4.166169 |
1 | 15,029 | G | A | 35 | 81,512 | 0.000429 | downstream_gene_variant,non_coding_transcript_exon_variant | -2.226965 |
1 | 15,038 | A | C | 1 | 77,374 | 0.000013 | downstream_gene_variant,splice_region_variant&non_coding_transcript_exon_variant | -6.90272 |
1 | 15,064 | G | A | 1 | 108,206 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.442346 |
1 | 15,090 | G | A | 13 | 113,228 | 0.000115 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | 0.963084 |
1 | 15,141 | T | G | 2 | 134,288 | 0.000015 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.160546 |
1 | 15,150 | C | T | 1 | 134,962 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.004377 |
1 | 15,161 | G | C | 2 | 135,994 | 0.000015 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.239427 |
1 | 15,164 | C | G | 1 | 136,182 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.521807 |
1 | 15,182 | C | G | 3 | 136,846 | 0.000022 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.291081 |
1 | 15,184 | A | C | 1 | 136,702 | 0.000007 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.626844 |
1 | 15,189 | C | T | 1,149 | 128,178 | 0.008964 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | 1.40442 |
1 | 15,207 | C | T | 320 | 123,478 | 0.002592 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | 0.703166 |
1 | 15,208 | G | A | 201 | 119,564 | 0.001681 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | 0.318087 |
1 | 15,211 | T | G | 8,427 | 71,424 | 0.117986 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -0.747057 |
1 | 15,216 | G | T | 1 | 113,222 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.274061 |
1 | 15,218 | G | A | 3 | 112,660 | 0.000027 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.537738 |
1 | 15,221 | G | C | 15 | 110,864 | 0.000135 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.290109 |
1 | 15,227 | T | G | 1 | 109,290 | 0.000009 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.411308 |
1 | 15,230 | C | T | 3 | 109,332 | 0.000027 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.382514 |
1 | 15,241 | G | T | 5 | 102,064 | 0.000049 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.414631 |
1 | 15,248 | G | A | 1 | 100,990 | 0.00001 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -0.658381 |
1 | 15,256 | T | C | 5 | 91,414 | 0.000055 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -0.986071 |
1 | 15,257 | G | A | 4 | 91,792 | 0.000044 | downstream_gene_variant,intron_variant&non_coding_transcript_variant | -1.508147 |